4-MeOA, 4-Methoxyamphetamine, PMA, 4-MeO-A, “Death”
Consolidated Research Chemicals offer a wide range of designer drugs and bio-based chemicals to quality-driven and environmentally-conscious customers around the globe.
Consequently, Consolidated Research Chemicals stands for premium quality and service excellence. We supply life science, food, drugs, flavor, fragrance, personal care, extraction and industrial companies with mission-critical products since 30 years.
Subsequently, as a major dealer on Chemical & Allied Products, we recommend you buy 4-MeOA, 4-Methoxyamphetamine, PMA, 4-MeO-A, “Death”. We are a professional research chemical supplier in United Kingdom, we have sold research chemical products since 30 years. we supply good and professional service.
para-Methoxyamphetamine (PMA), also known as 4-methoxyamphetamine (4-MA), is a designer drug of the amphetamine class with serotonergic effects. Unlike other similar drugs of this family, PMA does not produce stimulant, euphoriant, or entactogenic effects, and behaves more like an antidepressant in comparison, though it does have some psychedelic properties.
PMA has been found in tablets touted as MDMA (ecstasy) although its effects are markedly different compared to those of MDMA. The consequences of such deception have often included hospitalization and death for unwitting users.
PMA is commonly synthesized from anethole, the flavor compound of anise and fennel, mainly because the starting material for MDMA, safrole, has become less available due to law enforcement action, causing illicit drug manufacturers to use anethole as an alternative.
PMA acts as a selective serotonin releasing agent (SSRA) with weak effects on dopamine and norepinephrine transporters. Its EC50Tooltip half-maximal effective concentration values for induction of monoamine release are 166 nM for dopamine and 867 nM for norepinephrine in rat brain synaptosomes, whereas serotonin was not reported.
The drug has been found to robustly increase brain serotonin levels and to weakly increase brain dopamine levels in rodents in vivo. Relative to MDMA, PMA appears to be considerably less effective as a releaser of serotonin, with properties more akin to a serotonin reuptake inhibitor in comparison.
PMA has also been shown to act as a potent monoamine oxidase inhibitor (MAOI), specifically as a reversible inhibitor of the enzyme monoamine oxidase A (MAO-A) with no significant effects on monoamine oxidase B (MAO-B). The IC50Tooltip half-maximal inhibitory concentration of PMA for MAO-A inhibition has been reported to be 300 to 600 nM.
You can buy 4-MeOA, 4-Methoxyamphetamine, PMA, 4-MeO-A with a purity of 98%>! Buy 4-MeOA, 4-Methoxyamphetamine in our store without any problems. The product is intended for research purposes only and is not sold for consumption purposes.
By ordering / purchasing 4-MeOA, 4-Methoxyamphetamine, PMA, 4-MeO-A you automatically agree with our general terms and conditions that you only purchase the product for research purposes and that you do not use the product for other purposes.
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