Tianeptine Sulfate Powder

Tianeptine Sulfate Powder

Consolidated Research Chemicals offer a wide range of designer drugs and bio-based chemicals to quality-driven and environmentally-conscious customers around the globe.

Consequently, Consolidated Research Chemicals stands for premium quality and service excellence. We supply life science, food, drugs, flavor, fragrance, personal care, extraction and industrial companies with mission-critical products since 30 years.

Subsequently, as a major dealer on Chemical & Allied Products, here is Tianeptine Sulfate Powder . We are a professional research chemical supplier in United Kingdom, we have sold research chemical products since 30 years. we supply good and professional service.

Conclusively, we recommend you buy Tianeptine Sulfate Powder .

Tianeptine sodium salt is an atypical antidepressant. Tianeptine Sulfate Powder is a moderate-intensity agonist of the μ-opioid receptor (MOR), and to a lesser extent, is an agonist of the δ-opioid receptor (DOR).

Tianeptine sodium salt is a glutamate modulator that can enhance AMPA receptor and antagonize NMDA receptor. Tianeptine Sulfate Powder increases sensitivity of the α1 adrenergic receptor, which only manifests in chronic treatment.

Tianeptine Sulfate Powder exerts neuroprotective effects under stress/inflammation-induced conditions, exhibiting anti-inflammatory and antioxidant properties. Tianeptine Sulfate Powder t inhibits MMP-9 by suppressing the PI3K/Akt-mediated NF-κB pathway. Tianeptine Sulfate Powder can be used to alleviate symptoms of depression and anxiety, but does not cause sedative effects.

Tianeptine Sulfate Powder inhibits the polarization of microglia/macrophages to a pro-inflammatory (M1) phenotype by stimulating MOR, and increases the activity of antioxidant enzymes such as superoxide dismutase (SOD) and catalase, thereby alleviating oxidative stress damage.

Tianeptine Sulfate Powder can increase BDNF and NGF levels in brain regions such as the hippocampus and amygdala, and promote neurogenesis in the dentate gyrus of the hippocampus.

Tianeptine Sulfate Powder significantly reduces hypoxia-induced LDH release in rat embryonic cortical neurons.

Tianeptine Sulfate Powder does not reduce neuronal apoptosis induced directly by NMDA (HY-17551), but shows a slight but significant protective effect in the presence of IL-1β in mouse cortical neurons.
Tianeptine Sulfate Powder demonstrates low cardiotoxicity and minimal risk of CYP-mediated drug-drug interactions (DDIs).

Tianeptine Sulfate Powder (125-500 µM, 24 h) suppresses TNF-α-induced expression of MMP-9 in human carcinoma cells MDA-MB-231 via suppression of the PI3K/Akt-mediated NF-κB pathway.

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